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ERA (Endometrial Receptivity Analysis)

For a successful pregnancy in IVF (In Vitro Fertilization), a fertilized egg (embryo) needs to implant successfully at the right time in the lining of the uterus (endometrium). The Endometrial Receptivity Analysis (ERA) is a specialized test that helps determine the optimal timing for embryo transfer during an IVF cycle. It analyzes the gene expression of the endometrial tissue to know its receptivity for implantation.

Pre-Procedure Outline:

One can consider endoscopic surgeries for gynaecological problems because they offer several benefits compared to traditional open surgeries for the following merits.

Treatment Flowchart

STEP 1: Mock IVF Cycle

Hormonal Stimulation done to mimic egg development.

STEP 2: Endometrial Biopsy

A small sample of the uterus lining is collected for the test.

STEP 3: Sample Processing

The sample is processed for analysis.

STEP 4: Genetic Analysis

Gene's expression of the uterus lining tissue is analysed.

STEP 5: Results and Interpretation

Potential Decision pointers & outcomes:

Receptive: Uterus is ready

Pre-receptive: Uterus is not ready yet

Post-Receptive: The time is passed for implantation

Depending on the results, further investigations would be taken place

How it works?

Preimplantation Genetic Screening (PGS) assesses embryo chromosomes in IVF to select healthy embryos for transfer, enhancing the chances of successful implantation and reducing risks of miscarriage and birth defects.

Potential Proceedings After USG Findings:

A. Further Diagnostic Tests:

If abnormalities are detected, additional tests (e.g., blood tests, biopsies) may be recommended to gather more information.

B. Treatment Planning:

Based on the findings, a treatment plan may be developed. This could include medications, lifestyle modifications, or surgical interventions.

C. Monitoring:

Regular USG scans may be scheduled to monitor the progress of a condition or the effectiveness of a treatment.

Who can be benefitted?

USG is beneficial for a wide range of patients, including:

Patients with a history of recurrent miscarriages.

Women who are over 35 years old are considered advanced mothers.

Couples known to be at risk of genetic disorders.

Patients with unexplained infertility.

What are the benefits of USG?

  • Personalized timing for embryo transfer.

  • Reduced risk of failed transfers.

  • Increased chances of successful pregnancy.

  • Enhanced IVF success rates.

  • Minimally invasive procedure.

  • Tailored guidance for treatment decisions.

Post Procedure Outline:

ERA can be a valuable tool to optimize your IVF journey and increase your chances of achieving a successful pregnancy. ERA can help avoid unnecessary embryo transfers in cycles where the endometrium is not receptive. By transferring embryos at the optimal time, ERA can potentially increase the chances of a successful pregnancy.

Here at Freya, we believe in personalized care and utilizing the latest advancements in reproductive technology.

FAQ’s

  • By identifying the most receptive window for embryo transfer, ERA can enhance the success rates of IVF by ensuring that embryos are implanted at the optimal time for successful pregnancy.

  • Women who have experienced multiple failed IVF cycles or recurrent implantation failure may benefit from ERA to identify the best window of receptivity for successful embryo implantation.

  • ERA is a minimally invasive procedure with a low risk of complications, as it involves a simple endometrial biopsy to assess receptivity.

  • ERA can personalize the timing of embryo transfer based on an individual's unique receptivity pattern, increasing the chances of successful implantation and pregnancy.

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